I do get the impression that some people confuse "I really want that song to be played" with "They're likely to play that song".
I'd absolutely love them to open with Watcher, even an instrumental version, and close with The Knife. They could play two hours of improvisational jam based around Whoudnnit in between and I'd still have a blast. But I am realistic enough to understand that is *extremely* unlikely. They've stated they are not "dusting off" The Knife, and the indications are that they may have rehearsed Watcher but it didn't make the cut.
Realistically they're going to play Invisible Touch, Mama, Land Of Confusion, That's All. Not only are they the most familiar "hits", all but one has been heard in the teaser videos. They'll likely have a couple of better known hits from WDC too. And Follow You, Follow Me. They'll play the songs Nic has talked about - Apocalypse, Home By The Sea, Abacab.
Knowing Genesis there may be one genuine surprise...though that might be the aforementioned Apocalypse.
I do think we need to look at songs that *they* enjoy playing night after night....not simply our own personal wish lists. I don't know why they poo-pooed the idea of closing with the short version of The Knife, but they did...back in march 2020. Maybe they just don't enjoy it any more? Despite it being loved by most fans of 70s Genesis and a real rocker of a song that the fans of the hits can probably get behind too...and only being a few minutes if they don't. If Mike, Tony and Phil don't specifically enjoy it....they're not going to spend endless hours rehearsing and playing it.