Even if they forego the actual box, I'd love to see the surround mixes re-released for those that didn't get them the first time around. It's hard to believe it's been 12-13 years since those sets came out, so I don't think any complaints of "double dipping" would be particularly valid.
I think the biggest stumbling block is that there still isn't a truly agreed upon audiophile format, so choosing one is going to limit sales potential. There was a lot of push back in 2007 from folks that didn't have 5.1 home theater systems. DVD-A was dismissed as inferior because Europe got SACD. But SACD is an even smaller niche market than it was, and it seems (based on more recent audio releases) that 5.1 in a totally audio format isn't very popular anymore. Now that vinyl is seeing a big resurgence it splits the audiophile market even more.
MP3 is easy and it pleases the masses because it is able to go where the listener goes. None of the hi rez formats do that well, they're all dependent on equipment and that limits how the consumer will consume it.
It seems like Genesis is trying to build up some momentum with the impending tour but I fear it might be a bit of an uphill climb to convince the record company to get on board such a large project.